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Clinical supervision remains essential to mitigate these risks

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Molecular mechanisms of GLP-1 agonists for neuroprotection GLP-1 receptors are functionally expressed in insulin-releasing neuroglia form cells in the rat cerebral cortex, and hyperglycemia significantly increases GLP-1 receptor expression

The ASCO GI 2026 data suggest that GLP-1 therapy may be particularly relevant for metabolically high-risk populations, including individuals with obesity, insulin resistance, or type 2 diabetesgroups that now account for a substantial proportion of colorectal cancer burden